"Adult"

Ethnic differences in arterial responses and inflammatory markers in Afro-Caribbean and Caucasian subjects.
OBJECTIVE: Small vessel disease is more common in Afro-Caribbeans than Caucasians. We investigated underlying differences in metabolic, …
Lalit Kalra, Curtis Rambaran, Philip Chowienczyk, David Goss, Ian Hambleton, James Ritter, Ajay Shah, Rainford Wilks, Terrence Forrester
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Incidence and natural history of proliferative sickle cell retinopathy: observations from a cohort study.
OBJECTIVE: To describe the incidence, prevalence, and natural history of proliferative sickle cell retinopathy (PSR). DESIGN: …
Susan M. Downes, Ian R. Hambleton, Elaine L. Chuang, Noemi Lois, Graham R. Serjeant, Alan C. Bird
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Fecundity and pregnancy outcome in a cohort with sickle cell-haemoglobin C disease followed from birth.
OBJECTIVE: To compare pregnancy outcome in sickle cell-haemoglobin C (SC) disease with that in homozygous sickle cell (SS) disease and …
Graham R. Serjeant, Ian Hambleton, Minerva Thame
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Outcome of pregnancy in homozygous sickle cell disease.
OBJECTIVE: Previous reports on pregnancy in homozygous sickle cell (SS) disease are biased by hospital-based, more severely affected …
Graham R. Serjeant, Luana Look Loy, Mark Crowther, Ian R. Hambleton, Minerva Thame
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Chronic leg ulceration in homozygous sickle cell disease: the role of venous incompetence.
Chronic leg ulceration is a common cause of morbidity in Jamaican patients with homozygous sickle cell (SS) disease. Ulcers heal more …
Andrea Clare, Michael FitzHenley, June Harris, Ian Hambleton, Graham R. Serjeant
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Haematological response to parvovirus B19 infection in homozygous sickle-cell disease.
Infection with human parvovirus B19 is known to cause aplastic crises in patients with homozygous sickle-cell disease. We studied the …
B. E. Serjeant, I. R. Hambleton, S. Kerr, C. G. Kilty, G. R. Serjeant
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Red cell antibodies in patients with homozygous sickle cell disease: a comparison of patients in Jamaica and the United Kingdom.
The transfusion history and frequency of red cell antibodies in patients with homozygous sickle cell (SS) disease have been compared in …
A. Olujohungbe, I. Hambleton, L. Stephens, B. Serjeant, G. Serjeant
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Psychological distress and coping in sickle cell disease: comparison of British and Jamaican attitudes.
OBJECTIVE: To investigate possible differences in coping mechanisms in the painful crisis between Jamaican and London patients with …
V. J. Thomas, I. Hambleton, G. Serjeant
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RBC transfusion in sickle cell anemia (HbSS): experience from the Jamaican Cohort Study.
BACKGROUND: RBC transfusion is widely advocated in the management of sickle cell anemia (SCA), but it carries potentially serious …
J. R. Thame, I. R. Hambleton, G. R. Serjeant
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Survival estimates for patients with homozygous sickle-cell disease in Jamaica: a clinic-based population study.
BACKGROUND: Information about life expectancy of patients with homozygous sickle-cell disease is needed for research and patient …
K. J. Wierenga, I. R. Hambleton, N. A. Lewis
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