"Anemia"

Albuminuria and renal function in homozygous sickle cell disease: observations from a cohort study.
BACKGROUND: The glomerular filtration rate (GFR) in homozygous sickle cell (SS) disease is supranormal in childhood but falls steeply …
Joanne Thompson, Marvin Reid, Ian Hambleton, Graham R. Serjeant
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Elderly survivors with homozygous sickle cell disease.
Graham R. Serjeant, Douglas R. Higgs, Ian R. Hambleton
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Predicted declines in sickle allele frequency in Jamaica using empirical data.
The high frequency of the sickle allele in some parts of Africa is understood to be a consequence of high malarial endemicity. One …
N. A. Hanchard, I. Hambleton, R. M. Harding, C. A. McKenzie
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The prevalence of marijuana smoking in young adults with sickle cell disease: a longitudinal study.
BACKGROUND: The active ingredients of marijuana may have beneficial properties in the treatment of chronic pain and inflammation and is …
J. Knight-Madden, N. Lewis, I. R. Hambleton
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Comment on: Loureiro & Rozenfeld \"Epidemiology of sickle cell disease hospital admissions in Brazil\".
Klaas J. J. Wierenga, Ian R. Hambleton
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Incidence and natural history of proliferative sickle cell retinopathy: observations from a cohort study.
OBJECTIVE: To describe the incidence, prevalence, and natural history of proliferative sickle cell retinopathy (PSR). DESIGN: …
Susan M. Downes, Ian R. Hambleton, Elaine L. Chuang, Noemi Lois, Graham R. Serjeant, Alan C. Bird
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The frequency of the sickle allele in Jamaica has not declined over the last 22 years.
The ‘malaria hypothesis’ predicts that the frequency of the sickle allele, which is high in malaria-endemic African …
N. A. Hanchard, I. Hambleton, R. M. Harding, C. A. McKenzie
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Outcome of pregnancy in homozygous sickle cell disease.
OBJECTIVE: Previous reports on pregnancy in homozygous sickle cell (SS) disease are biased by hospital-based, more severely affected …
Graham R. Serjeant, Luana Look Loy, Mark Crowther, Ian R. Hambleton, Minerva Thame
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Identifying homozygous sickle cell disease when neonatal screening is not available: a clinic-based observational study.
OBJECTIVES: Life-threatening clinical complications can occur in the first years of life in people with homozygous sickle cell disease. …
I. R. Hambleton, K. J. J. Wierenga
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Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease.
BACKGROUND: Bronchodilators are used to treat bronchial hyper-responsiveness in asthma. Bronchial hyper-responsiveness may be a …
J. A. Knight-Madden, I. R. Hambleton
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