"Case-Control Studies"

A preliminary examination of the effects of genetic variants of redox enzymes on susceptibility to oedematous malnutrition and on percentage cytotoxicity in response to oxidative stress in vitro.
BACKGROUND: The causes of oedematous vs non-oedematous childhood malnutrition (OM vs NOM) remain elusive. It is possible that inherited …
K. G. Marshall, K. Swaby, K. Hamilton, S. Howell, R. C. Landis, I. R. Hambleton, M. Reid, H. Fletcher, T. Forrester, C. A. McKenzie
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Pattern of pregnancy weight gain in homozygous sickle cell disease and effect on birth size.
OBJECTIVE: To assess pregnancy weight gain and newborn anthropometry in mothers with homozygous sickle cell (SS) disease and normal …
M. Thame, J. Lewis, I. Hambleton, H. Trotman, G. Serjeant
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All-cause mortality after diabetes-related amputation in Barbados: a prospective case-control study.
OBJECTIVE: To determine the mortality rate after diabetes-related lower-extremity amputation (LEA) in an African-descent Caribbean …
Ian R. Hambleton, Ramesh Jonnalagadda, Christopher R. Davis, Henry S. Fraser, Nish Chaturvedi, Anselm J. Hennis
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Risk factors for breast cancer in a black population--the Barbados National Cancer Study.
The Barbados National Cancer Study (BNCS) is a nationwide case-control study investigating environmental and genetic factors for breast …
Barbara Nemesure, Suh-Yuh Wu, Ian R. Hambleton, M. Cristina Leske, Anselm J. Hennis
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Voices of the women: feedback from women of child-bearing age who are living with HIV can help improve efficacy of psychosocial interventions.
BACKGROUND: We hypothesized that voluntary counselling and testing during pregnancy are necessary but not sufficient to provide the …
P. D. Weller, I. R. Hambleton, C. Chambers, S. Bain, C. D. C. Christie, B. Bain
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The mechanisms of low birth weight in infants of mothers with homozygous sickle cell disease.
OBJECTIVE: A low mean birth weight is a constant finding in pregnancies of women with homozygous sickle cell disease. The factors …
Minerva Thame, Jillian Lewis, Helen Trotman, Ian Hambleton, Graham Serjeant
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Outcome of pregnancy in homozygous sickle cell disease.
OBJECTIVE: Previous reports on pregnancy in homozygous sickle cell (SS) disease are biased by hospital-based, more severely affected …
Graham R. Serjeant, Luana Look Loy, Mark Crowther, Ian R. Hambleton, Minerva Thame
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Chronic leg ulceration in homozygous sickle cell disease: the role of venous incompetence.
Chronic leg ulceration is a common cause of morbidity in Jamaican patients with homozygous sickle cell (SS) disease. Ulcers heal more …
Andrea Clare, Michael FitzHenley, June Harris, Ian Hambleton, Graham R. Serjeant
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Postsplenectomy course in homozygous sickle cell disease.
OBJECTIVE: To determine whether children with homozygous sickle cell (SS) disease and splenectomy are at greater risk of death, …
J. G. Wright, I. R. Hambleton, P. W. Thomas, N. D. Duncan, S. Venugopal, G. R. Serjeant
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Population-based study of risk of venous thromboembolism associated with various oral contraceptives.
BACKGROUND: Four studies published since December, 1995, reported that the incidence of venous thromboembolism (VTE) was higher in …
R. D. Farmer, R. A. Lawrenson, C. R. Thompson, J. G. Kennedy, I. R. Hambleton
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