"Cohort Studies"

Impact of common cardio-metabolic risk factors on fatal and non-fatal cardiovascular disease in Latin America and the Caribbean: an individual-level pooled analysis of 31 cohort studies.

BACKGROUND: Estimates of the burden of cardio-metabolic risk factors in Latin America and the Caribbean (LAC) rely on relative risks …

CC-LAC

Causes of death and early life determinants of survival in homozygous sickle cell disease: The Jamaican cohort study from birth.

Globally, the majority of persons born with sickle cell disease do not have access to hydroxyurea or more expensive interventions. The …

Graham R. Serjeant, Nicki Chin, Monika R. Asnani, Beryl E. Serjeant, Karlene P. Mason, Ian R. Hambleton, Jennifer M. Knight-Madden

Educational health disparities in hypertension and diabetes mellitus among African descent populations in the Caribbean and the USA: a comparative analysis from the Spanish town cohort (Jamaica) and the Jackson heart study (USA).

BACKGROUND: Studies have suggested that social inequalities in chronic disease outcomes differ between industrialized and developing …

Aurelian Bidulescu, Trevor S. Ferguson, Ian Hambleton, Novie Younger-Coleman, Damian Francis, Nadia Bennett, Michael Griswold, Ervin Fox, Marlene MacLeish, Rainford Wilks, E. Nigel Harris, Louis W. Sullivan

The Effect of Psychosocial and Neuropsychiatric Factors on Medication Adherence in a Cohort of Women With Systemic Lupus Erythematosus.

BACKGROUND: Medication adherence in systemic lupus erythematosus (SLE) reduces disease activity and the risk of flares. OBJECTIVES: We …

Cindy Flower, Ian Hambleton, Mike Campbell

Clinical findings associated with homozygous sickle cell disease in the Barbadian population--do we need a national SCD registry?

BACKGROUND: Comprehensive care in homozygous sickle cell disease (HbSS) entails universal neonatal screening and subsequent monitoring …

Kim R. Quimby, Stephen Moe, Ian Sealy, Christopher Nicholls, Ian R. Hambleton, R. Clive Landis

Homozygous sickle cell disease in Uganda and Jamaica a comparison of Bantu and Benin haplotypes.

OBJECTIVE: To compare the haematological and clinical features of homozygous sickle cell (SS) disease in Bantu and Benin haplotypes in …

C. Ndugwa, D. Higgs, C. Fisher, I. Hambleton, K. Mason, B. E. Serjeant, G. R. Serjeant

Are women who work in bars, guesthouses and similar facilities a suitable study population for vaginal microbicide trials in Africa?

BACKGROUND: A feasibility study was conducted to investigate whether an occupational at-risk cohort of women in Mwanza, Tanzania are a …

Andrew Vallely, Ian R. Hambleton, Stella Kasindi, Louise Knight, Suzanna C. Francis, Tobias Chirwa, Dean Everett, Charles Shagi, Claire Cook, Celia Barberousse, Deborah Watson-Jones, John Changalucha, David Ross, Richard J. Hayes

Microbicides development program, Tanzania-baseline characteristics of an occupational cohort and reattendance at 3 months.

OBJECTIVES: To determine baseline characteristics of an occupational cohort of women in Mwanza City, Tanzania, and factors associated …

Andrew Vallely, Stella Kasindi, Ian R. Hambleton, Louise Knight, Tobias Chirwa, Rebecca Balira, John Changalucha, Deborah Watson-Jones, Dean Everett, Awene Gavyole, Jocelyn Moyes, Mar Pujades-Rodríguez, David A. Ross, Richard J. Hayes

Albuminuria and renal function in homozygous sickle cell disease: observations from a cohort study.

BACKGROUND: The glomerular filtration rate (GFR) in homozygous sickle cell (SS) disease is supranormal in childhood but falls steeply …

Joanne Thompson, Marvin Reid, Ian Hambleton, Graham R. Serjeant

Fecundity and pregnancy outcome in a cohort with sickle cell-haemoglobin C disease followed from birth.

OBJECTIVE: To compare pregnancy outcome in sickle cell-haemoglobin C (SC) disease with that in homozygous sickle cell (SS) disease and …

Graham R. Serjeant, Ian Hambleton, Minerva Thame