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Significance of fever in Jamaican patients with homozygous sickle cell disease.
OBJECTIVE: To investigate the cause and outcome of high fever in Jamaican children with homozygous sickle cell disease. DESIGN: …
K. J. Wierenga, I. R. Hambleton, R. M. Wilson, H. Alexander, B. E. Serjeant, G. R. Serjeant
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Psychological distress among younger siblings of patients with homozygous sickle cell disease in the Jamaican cohort study.
The presence of a chronically ill family member may adversely affect the psychological health of siblings. This study used the General …
K. Foster-Williams, I. R. Hambleton, C. Hilton, G. R. Serjeant
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Gallstones in sickle cell disease: observations from The Jamaican Cohort study.
The prevalence, incidence, risk factors, clinical associations, and morbidity of gallstones were studied in 311 patients with …
T. M. Walker, I. R. Hambleton, G. R. Serjeant
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Recurrent infections in homozygous sickle cell disease.
The characteristics of 214 episodes of invasive bacterial infection among 176 patients with homozygous sickle cell (SS) disease were …
S. A. Magnus, I. R. Hambleton, F. Moosdeen, G. R. Serjeant
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Postsplenectomy course in homozygous sickle cell disease.
OBJECTIVE: To determine whether children with homozygous sickle cell (SS) disease and splenectomy are at greater risk of death, …
J. G. Wright, I. R. Hambleton, P. W. Thomas, N. D. Duncan, S. Venugopal, G. R. Serjeant
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Day-care management of sickle cell painful crisis in Jamaica: a model applicable elsewhere?
In the U.K. and the U.S.A., painful crises account for 80-90% of sickle-related hospital admissions, with average durations of 5-11 d. …
M. A. Ware, I. Hambleton, I. Ochaya, G. R. Serjeant
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Population-based study of risk of venous thromboembolism associated with various oral contraceptives.
BACKGROUND: Four studies published since December, 1995, reported that the incidence of venous thromboembolism (VTE) was higher in …
R. D. Farmer, R. A. Lawrenson, C. R. Thompson, J. G. Kennedy, I. R. Hambleton
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Oral contraceptive switching patterns in the United Kingdom: an important potential confounding variable in studies of venous thromboembolism.
OBJECTIVE: To investigate whether patients changing from their current oral contraceptive (OC) are preferentially switched to …
R. D. Farmer, R. A. Lawrenson, I. R. Hambleton
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