Ian Hambleton
Ian Hambleton
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"Fetal Hemoglobin"
A Plea for the Newborn Diagnosis of Hb S-Hereditary Persistence of Fetal Hemoglobin.
The gene for hereditary persistence of fetal hemoglobin (HPFH) in the Caribbean is much more common than previously estimated. To avoid …
Graham R. Serjeant
,
Beryl E. Serjeant
,
Ian R. Hambleton
,
Matthew Oakley
,
Swee Lay Thein
,
Barnaby Clark
Cite
DOI
Homozygous sickle cell disease in Uganda and Jamaica a comparison of Bantu and Benin haplotypes.
OBJECTIVE: To compare the haematological and clinical features of homozygous sickle cell (SS) disease in Bantu and Benin haplotypes in …
C. Ndugwa
,
D. Higgs
,
C. Fisher
,
I. Hambleton
,
K. Mason
,
B. E. Serjeant
,
G. R. Serjeant
Cite
Hb S-β-thalassemia: molecular, hematological and clinical comparisons.
Clinical and hematological features are presented for 261 patients with identified β-thalassemia (β-thal) mutations. Mutations causing …
Graham R. Serjeant
,
Beryl E. Serjeant
,
Raphael A. Fraser
,
Ian R. Hambleton
,
Douglas R. Higgs
,
Andreas E. Kulozik
,
Alan Donaldson
Cite
DOI
The changing face of homozygous sickle cell disease: 102 patients over 60 years.
Earlier reports on homozygous sickle cell (SS) disease have been biased by severely affected cases. The Jamaican clinic which seeks to …
G. R. Serjeant
,
B. E. Serjeant
,
K. P. Mason
,
I. R. Hambleton
,
C. Fisher
,
D. R. Higgs
Cite
DOI
Ethnic differences in F cell levels in Jamaica: a potential tool for identifying new genetic loci controlling fetal haemoglobin.
High levels of fetal haemoglobin (HbF) are protective in beta-haemoglobinopathies. The proportion of erythrocytes containing HbF …
Lisa E. Creary
,
Colin A. McKenzie
,
Stephan Menzel
,
Neil A. Hanchard
,
Veronica Taylor
,
Ian Hambleton
,
Tim D. Spector
,
Terrence E. Forrester
,
Swee Lay Thein
Cite
DOI
Elderly survivors with homozygous sickle cell disease.
Graham R. Serjeant
,
Douglas R. Higgs
,
Ian R. Hambleton
Cite
DOI
Newborn screening for sickle cell disease in Brazil: the Campinas experience.
Newborn screening for sickle cell disease commenced in 1992 in Sao Paulo State and by the end of 2000, the programme covered 78 …
S. Brandelise
,
V. Pinheiro
,
C. S. Gabetta
,
I. Hambleton
,
B. Serjeant
,
G. Serjeant
Cite
DOI
Peripheral vascular response to mild indirect cooling in patients with homozygous sickle cell (SS) disease and the frequency of painful crisis.
In homozygous sickle cell (SS) disease, skin cooling is a common precipitating factor of the painful crisis which is associated with …
J. Mohan
,
J. M. Marshall
,
H. L. Reid
,
P. W. Thomas
,
I. Hambleton
,
G. R. Serjeant
Cite
DOI
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