Ian Hambleton
Ian Hambleton
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"Hemoglobins"
Intravenous infusion of haptoglobin for the prevention of adverse clinical outcome in Sickle Cell Disease.
Sickle Cell Disease (SCD) is a genetic condition which manifests as altered hemoglobin (Hb) protein that can aggregate under hypoxic …
Kim R. Quimby
,
Ian R. Hambleton
,
R. Clive Landis
Cite
DOI
Hb S-β-thalassemia: molecular, hematological and clinical comparisons.
Clinical and hematological features are presented for 261 patients with identified β-thalassemia (β-thal) mutations. Mutations causing …
Graham R. Serjeant
,
Beryl E. Serjeant
,
Raphael A. Fraser
,
Ian R. Hambleton
,
Douglas R. Higgs
,
Andreas E. Kulozik
,
Alan Donaldson
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DOI
Elderly survivors with homozygous sickle cell disease.
Graham R. Serjeant
,
Douglas R. Higgs
,
Ian R. Hambleton
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DOI
Psychological distress among younger siblings of patients with homozygous sickle cell disease in the Jamaican cohort study.
The presence of a chronically ill family member may adversely affect the psychological health of siblings. This study used the General …
K. Foster-Williams
,
I. R. Hambleton
,
C. Hilton
,
G. R. Serjeant
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Comparison of responses evoked by mild indirect cooling and by sound in the forearm vasculature in patients with homozygous sickle cell disease and in normal subjects.
In normal individuals, novel or noxious stimuli commonly evoke the pattern of the alerting or defence response which includes cutaneous …
J. S. Mohan
,
J. M. Marshall
,
H. L. Reid
,
P. W. Thomas
,
I. Hambleton
,
G. R. Serjeant
Cite
DOI
Peripheral vascular response to mild indirect cooling in patients with homozygous sickle cell (SS) disease and the frequency of painful crisis.
In homozygous sickle cell (SS) disease, skin cooling is a common precipitating factor of the painful crisis which is associated with …
J. Mohan
,
J. M. Marshall
,
H. L. Reid
,
P. W. Thomas
,
I. Hambleton
,
G. R. Serjeant
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DOI
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