"Humans"

Ethnic differences in arterial responses and inflammatory markers in Afro-Caribbean and Caucasian subjects.
OBJECTIVE: Small vessel disease is more common in Afro-Caribbeans than Caucasians. We investigated underlying differences in metabolic, …
Lalit Kalra, Curtis Rambaran, Philip Chowienczyk, David Goss, Ian Hambleton, James Ritter, Ajay Shah, Rainford Wilks, Terrence Forrester
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Incidence and natural history of proliferative sickle cell retinopathy: observations from a cohort study.
OBJECTIVE: To describe the incidence, prevalence, and natural history of proliferative sickle cell retinopathy (PSR). DESIGN: …
Susan M. Downes, Ian R. Hambleton, Elaine L. Chuang, Noemi Lois, Graham R. Serjeant, Alan C. Bird
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Fecundity and pregnancy outcome in a cohort with sickle cell-haemoglobin C disease followed from birth.
OBJECTIVE: To compare pregnancy outcome in sickle cell-haemoglobin C (SC) disease with that in homozygous sickle cell (SS) disease and …
Graham R. Serjeant, Ian Hambleton, Minerva Thame
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The frequency of the sickle allele in Jamaica has not declined over the last 22 years.
The ‘malaria hypothesis’ predicts that the frequency of the sickle allele, which is high in malaria-endemic African …
N. A. Hanchard, I. Hambleton, R. M. Harding, C. A. McKenzie
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Anaesthesia for operative deliveries at the University Hospital of the West Indies: a change of practice.
There has been an increasing trend worldwide to use regional anaesthesia for operative deliveries. The Confidential Enquiry into …
A. Crawford-Sykes, M. Scarlett, I. R. Hambleton, M. Nelson, C. Rattray
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Triage decisions and outcome among the critically ill at the University Hospital of the West Indies.
The worldwide scarcity of intensive care therapy leads to the rationing of this expensive resource. This prospective study investigates …
R. Augier, I. R. Hambleton, H. Harding
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Historical and current predictors of self-reported health status among elderly persons in Barbados.
OBJECTIVE: To understand the relative contribution of past events and of current experiences as determinants of health status among the …
Ian R. Hambleton, Kadene Clarke, Hedy L. Broome, Henry S. Fraser, Farley Brathwaite, Anselm J. Hennis
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Antiretroviral drug therapy in HIV-infected Jamaican children.
BACKGROUND: The study describes a cohort of HIV-infected Jamaican children receiving antiretroviral therapy (ART) and reports the …
T. Evans-Gilbert, R. Pierre, J. C. Steel-Duncan, B. Rodriguez, S. Whorms, I. R. Hambleton, J. P. Figueroa, C. D. C. Christie
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CDC-defined diseases and opportunistic infections in Jamaican children with HIV/AIDS.
OBJECTIVE: To document the frequency of Centers for Disease Control and Prevention (CDC)-defined clinical conditions, opportunistic and …
R. Pierre, J. C. Steel-Duncan, T. Evans-Gilbert, B. Rodriguez, P. Palmer, M. F. Smikle, S. Whorms, I. Hambleton, J. P. Figueroa, C. D. C. Christie
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Socio-demographic characteristics of HIV-exposed and HIV-infected Jamaican children.
BACKGROUND: In the face of the continuing pandemic of HIV/AIDS, the burden of the disease is now largest in the resource-poor …
B. Rodriquez, J. C. Steel-Duncan, R. Pierre, T. Evans-Gilbert, I. Hambleton, P. Palmer, J. P. Figueroa, C. D. C. Christie
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