"Infant"

Newborn screening for abnormal haemoglobins in Jamaica: Practical issues in an island programme.
OBJECTIVE: To report the diagnostic challenges of newborn screening for abnormal haemoglobins. SETTING: Cord blood samples from 13 …
Serjeant, Graham R, Serjeant, Beryl E, Mason, Karlene P, Gibson, Felicea, Gardner, Ruth-Ann, Warren, Lansford, Hambleton, Ian R, Thein, Swee L, Happich, Margit
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COVID-19 in Children in the United States: Intensive Care Admissions, Estimated Total Infected, and Projected Numbers of Severe Pediatric Cases in 2020.
IMPORTANCE: A surge in severe cases of COVID-19 (coronavirus disease 2019) in children would present unique challenges for hospitals …
Elizabeth Barnett Pathak, Jason L. Salemi, Natasha Sobers, Janelle Menard, Ian R. Hambleton
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Causes of death and early life determinants of survival in homozygous sickle cell disease: The Jamaican cohort study from birth.
Globally, the majority of persons born with sickle cell disease do not have access to hydroxyurea or more expensive interventions. The …
Graham R. Serjeant, Nicki Chin, Monika R. Asnani, Beryl E. Serjeant, Karlene P. Mason, Ian R. Hambleton, Jennifer M. Knight-Madden
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A Plea for the Newborn Diagnosis of Hb S-Hereditary Persistence of Fetal Hemoglobin.
The gene for hereditary persistence of fetal hemoglobin (HPFH) in the Caribbean is much more common than previously estimated. To avoid …
Graham R. Serjeant, Beryl E. Serjeant, Ian R. Hambleton, Matthew Oakley, Swee Lay Thein, Barnaby Clark
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Predicting the burden of acute myocardial infarction in a country with limited resources: combining data from routine sources.
BACKGROUND: Prior to implementation of a national surveillance system for cardiovascular disease in Barbados, a small island state with …
Angela M. C. Rose, Nico R. S. Belgrave, Lauren Maul, Anselm J. M. Hennis, Rudy Delice, Ian R. Hambleton
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Clinical findings associated with homozygous sickle cell disease in the Barbadian population--do we need a national SCD registry?
BACKGROUND: Comprehensive care in homozygous sickle cell disease (HbSS) entails universal neonatal screening and subsequent monitoring …
Kim R. Quimby, Stephen Moe, Ian Sealy, Christopher Nicholls, Ian R. Hambleton, R. Clive Landis
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Diabetes in North America and the Caribbean: an update.
The North America and Caribbean (NAC) Region faces a high burden of diabetes. In 2013, the number of children (aged 0-14 years) with …
Samrawit F. Yisahak, Jessica Beagley, Ian R. Hambleton, K. M. Venkat Narayan
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Homozygous sickle cell disease in Uganda and Jamaica a comparison of Bantu and Benin haplotypes.
OBJECTIVE: To compare the haematological and clinical features of homozygous sickle cell (SS) disease in Bantu and Benin haplotypes in …
C. Ndugwa, D. Higgs, C. Fisher, I. Hambleton, K. Mason, B. E. Serjeant, G. R. Serjeant
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Systemic lupus erythematosus in an African Caribbean population: incidence, clinical manifestations, and survival in the Barbados National Lupus Registry.
OBJECTIVE: To assess the epidemiology, clinical features, and outcomes of systemic lupus erythematosus (SLE) in the predominantly …
Cindy Flower, Anselm J. M. Hennis, Ian R. Hambleton, George D. Nicholson, Matthew H. Liang
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A preliminary examination of the effects of genetic variants of redox enzymes on susceptibility to oedematous malnutrition and on percentage cytotoxicity in response to oxidative stress in vitro.
BACKGROUND: The causes of oedematous vs non-oedematous childhood malnutrition (OM vs NOM) remain elusive. It is possible that inherited …
K. G. Marshall, K. Swaby, K. Hamilton, S. Howell, R. C. Landis, I. R. Hambleton, M. Reid, H. Fletcher, T. Forrester, C. A. McKenzie
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