"Retrospective Studies"

Uptake of interventions, outcomes and challenges in caring for HIV-exposed infants in Kingston, Jamaica.
BACKGROUND: In a few Caribbean islands, prevention of mother-to-child transmission (pMTCT) of HIV with zidovudine prophylaxis has …
J. C. Steel-Duncan, R. Pierre, T. Evans-Gilbert, B. Rodriquez, M. F. Smikle, P. Palmer, S. Whorms, I. Hambleton, J. P. Figueroa, C. D. C. Christie
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Paravertebral anaesthesia for breast surgery an initial experience at the University Hospital of the West Indies.
Paravertebral blockade (PVB) is a regional anaesthetic technique that allows the injection of local anaesthetic agents into the …
A. M. Crawford-Sykes, D. E. Chin, I. R. Hambleton
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Identifying homozygous sickle cell disease when neonatal screening is not available: a clinic-based observational study.
OBJECTIVES: Life-threatening clinical complications can occur in the first years of life in people with homozygous sickle cell disease. …
I. R. Hambleton, K. J. J. Wierenga
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RBC transfusion in sickle cell anemia (HbSS): experience from the Jamaican Cohort Study.
BACKGROUND: RBC transfusion is widely advocated in the management of sickle cell anemia (SCA), but it carries potentially serious …
J. R. Thame, I. R. Hambleton, G. R. Serjeant
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Significance of fever in Jamaican patients with homozygous sickle cell disease.
OBJECTIVE: To investigate the cause and outcome of high fever in Jamaican children with homozygous sickle cell disease. DESIGN: …
K. J. Wierenga, I. R. Hambleton, R. M. Wilson, H. Alexander, B. E. Serjeant, G. R. Serjeant
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Recurrent infections in homozygous sickle cell disease.
The characteristics of 214 episodes of invasive bacterial infection among 176 patients with homozygous sickle cell (SS) disease were …
S. A. Magnus, I. R. Hambleton, F. Moosdeen, G. R. Serjeant
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Postsplenectomy course in homozygous sickle cell disease.
OBJECTIVE: To determine whether children with homozygous sickle cell (SS) disease and splenectomy are at greater risk of death, …
J. G. Wright, I. R. Hambleton, P. W. Thomas, N. D. Duncan, S. Venugopal, G. R. Serjeant
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Oral contraceptive switching patterns in the United Kingdom: an important potential confounding variable in studies of venous thromboembolism.
OBJECTIVE: To investigate whether patients changing from their current oral contraceptive (OC) are preferentially switched to …
R. D. Farmer, R. A. Lawrenson, I. R. Hambleton
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